His parents raised him and his siblings in Downingtown, Pennsylvania, where they were close to much of their extended family.
As a child, the family had a set time for breakfast and dinner, which all family members attended. These meals also included daily family devotions.
Jeremy was homeschooled until the 11th grade, when he began attending Downingtown West High School. During his last two years of high school, Jeremy began to get involved in the "weekend party scene". Jeremy played soccer while in high school, and was named Regional All-American as a Junior.
Jeremy met Ben and Jessa Seewald while they were visiting a friend in San Antonio, Texas and happened to attend a church fellowship at Jeremy's house. Jeremy struck up a friendship with Ben, and a couple months later when visiting Ben and Jessa, he was introduced to Jessa's younger sister, Jinger. As he began to get to know her, he started praying about pursuing a relationship with her. Shortly after, Jeremy went on a mission trip to Honduras with the Duggar family, where he spent more time with Jinger and discovered his interest in her was mutual. On December 11, 2015, he asked her father Jim Bob Duggar's permission to begin getting to know her more seriously. On June 2, 2016, Jeremy asked Jinger to officially begin a courtship with him on the front porch of her family's house in Springdale, Arkansas. On June 20, 2016, the couple announced that they were courting. Their courtship proposal was featured on the Counting On episode "A Courtship Begins".
On July 25, 2016, while on a trip to New York City, Jeremy took Jinger onto the rooftop of a building in Manhattan under the pretense of taking sunset photos together with Jeremy's photographer friend, James Song. He had arranged for a string quartet to be playing one of Jinger's favorite hymns, "Come Thou Font". It was there that he proposed to her. Their engagement was featured on the Counting On episode "Proposal in the City".
On November 5, 2016, Jeremy married Jinger Nicole Duggar at the Cathedral of the Ozarks at John Brown University in Siloam Springs, Arkansas. The wedding had around 1,000 guests. The couple shared their first kiss at the altar. The wedding was officiated by Jeremy's father Charles Vuolo. Jeremy's best man was his brother Charles. The groomsmen were Jinger's brother John-David, Jinger's brother-in-law Ben, and his friends Joshua Conway, James Song, Josue Soto, Tim White, Esteban, and two unknown friends. The ring bearer was Jinger's nephew Michael. Jinger's matron of honor was her sister Jessa. Her bridesmaids were her sisters Jana, Jill, Joy-Anna, and Johannah, her sister-in-law Anna, Jeremy's sister Valerie, and her friends Jennifer Hartono, Rebekah Kelly, and Kenzie Peters. The flower girl was Jinger's sister Josie. The ushers were Jinger's brothers Joseph, Josiah, Jedidiah, and Jeremiah. Their wedding was featured on the Counting On episodes "Jinger's Wedding" and "The Big Day".
For their honeymoon, Jeremy and Jinger went to Sydney, Australia. They visited the Sydney Opera House and Circular Quay, and tried stereotypical Australian activities, like boomerang throwing, didgeridoo playing, and grilling "shrimp on the barbie". They also spent time at a wildlife refuge. Their honeymoon was featured on the Counting On episode "A Honeymoon & a Courtship".
On January 3, 2018, Jeremy and Jinger announced that they were expecting their first child. The due date was later revealed to be July 20, 2018. On April 9, 2018, they revealed that they were expecting a girl. On July 19, 2018, Jeremy and Jinger announced that their daughter, Felicity Nicole, was born at 4:37 a.m. on July 19, 2018, at Methodist Hospital in San Antonio, Texas. She weighed 8 pounds and 3 ounces, and was 19 ½ inches long. Her birth was featured on the Counting On episode "Jinger Has a Baby".
The couple suffered a miscarriage on November 26, 2019. The miscarriage occurred the day after they had announced to their families that they were expecting what would have been their second child. They chose not to publicly speak about it at that time, but mentioned it while announcing their pregnancy with Evangeline. They named their miscarried child Halleli Grace. They announced their pregnancy on the Counting On episode "A Beautiful Miracle". They announced their miscarriage on the Counting On episode "Highs and Lows".
On May 28, 2020, Jeremy and Jinger announced that they were expecting their second child, a girl, due November 2020. The due date was later revealed to be November 19, 2020. On November 25, 2020, Jeremy and Jinger announced that their daughter, Evangeline Jo, was born at 11:26 p.m. on November 22, 2020, in Los Angeles, California. She weighed 7 pounds, and was 20 inches long. Her birth was featured on the Counting On episode "Another Girl for Jinger".
Jeremy begin attending Hartwick College in 2007, where he was studying business. In 2009, he transferred to Syracuse University for his senior year, where he was enrolled in the MBA program at the Martin J. Whitman School of Management. He continued to play soccer as a goalkeeper at both universities, and in 2010 was his team's captain. Jeremy graduated from Syracuse University in 2010.
On May 14, 2018, Jeremy announced that he had been accepted into the theological and pastoral studies program at The Master's Seminary. On May 8, 2022, Jeremy graduated with his Master of Divinity Degree. In 2025, Jeremy will graduate with his Doctor of Divinity Degree.
After graduating from college, Jeremy began playing with Finnish First Division side AC Oulu. In January 2012, he signed with the New York Red Bulls. Jeremy said of his time in New York, it "proved to be one of the most difficult, while simultaneously being one of the most fulfilling, that I had ever had. Soccer did not progress how I had foreseen but it was clear that God was molding and nurturing me. I could go into great detail on the particulars but, for the sake of brevity, will simply say that God humbled me beyond what I thought possible.". On November 19, 2012, the team declined his option for the next season. Jeremy went on to make a trial appearance with Finnish club HJK Helsinki in 2013 and was also offered a chance to join a North Carolina team for preseason training. Although Jeremy posted a blog post on March 6, 2013, claiming that he would be leaving soccer to pursue full-time ministry, later that month he announced on Twitter that he had signed a contract with the San Antonio Scorpions.
For a few years, Jeremy studied under Tim Conway of Grace Community Church in San Antonio, Texas. On March 5, 2016, he was ordained a pastor at Grace Community Church in Laredo, Texas. Around this time, Jeremy officially became the pastor of GCC. In 2019, Jeremy transferred to Grace Community Church in Sun Valley, California.
Jeremy helps out with his mother Diana's charity SWAN 4 Kids in Lancaster, Pennsylvania.
On January 16, 2008, Jeremy was arrested for harassing a police officer in Oneonta, New York. According to the arrest record, which was obtained and published by InTouch Magazine in June 2016, Jeremy "was acting belligerent and shouting obscenities". He was held overnight and fined $250.
Jeremy was the officiant at his friends Patrick Powers and Kirsten Hermine's wedding on September 29, 2018.
He was the officiant at his friends Cade Foehner and Gabby Barrett's wedding on October 5, 2019.